Anaphylaxis occurs when a massive release of immune mediators — including histamine, prostaglandins, and leukotrienes — triggers a systemic reaction affecting multiple organ systems simultaneously. Common triggers include foods (peanuts, tree nuts, shellfish, fish, milk, eggs), medications (antibiotics, NSAIDs), insect venom (bee and wasp stings), latex, and exercise. In some cases, no trigger is identified (idiopathic anaphylaxis).
Common Signs & Symptoms
- Hives, flushing, or itching of the skin
- Swelling of the lips, tongue, throat, or face
- Difficulty breathing, wheezing, or stridor
- Drop in blood pressure causing dizziness or loss of consciousness
- Rapid or weak pulse
- Nausea, vomiting, or abdominal cramps
- Feeling of doom or extreme anxiety
How We Diagnose
Following an anaphylactic episode, our allergists conduct a comprehensive workup that includes a detailed history of the reaction, allergy skin testing and specific IgE blood testing for suspected triggers, and serum tryptase measurement to evaluate for underlying conditions such as mastocytosis that increase anaphylaxis risk.
Treatment Options
Our management strategy includes prescribed injectable epinephrine (EpiPen or generic equivalent) for all at-risk patients, a written Anaphylaxis Emergency Action Plan, education for patients, families, schools, and employers, venom immunotherapy for bee/wasp sting allergy (the only treatment that can prevent anaphylaxis in insect-allergic individuals), and drug desensitization protocols when essential medications must be continued.
Ready to Schedule?
Do not face anaphylaxis risk without a clear plan. Contact South Bay Allergy and Asthma Group to schedule a post-anaphylaxis evaluation and protect yourself with the right tools and knowledge. Call us at (408) 286-1707 or request an appointment online.